For casters and hybrid builds in Diablo IV, resource management is crucial to Diablo 4 Items maintain a steady flow of abilities while avoiding running out of resources during intense combat. Focusing on resource generation, cost reduction, and resource regeneration allows you to sustain your spells and abilities more effectively. Here are some resource management affix combinations to try for casters and hybrid builds:

1. Cooldown Reduction + Resource Generation
Cooldown Reduction: Reduces the cooldown of your abilities, allowing you to use your powerful spells more often.

Resource Generation: Increases the rate at which you generate your main resource (e.g., Mana, Fury, etc.), enabling you to keep casting your abilities without running out of resources.

Why it works: The combination of cooldown reduction and resource generation ensures you can spam your abilities more often while managing your resources effectively. This is especially useful for casters who rely on quick spell casts to stay efficient in battle.

2. Mana Cost Reduction + Increased Mana Pool
Mana Cost Reduction: Reduces the resource cost of your abilities, allowing you to cast spells more efficiently without draining your mana pool too quickly.

Increased Mana Pool: Expands your mana pool, letting you cast more abilities before running out of mana.

Why it works: This combination is perfect for casters who have high mana cost abilities. The mana cost reduction allows you to cast spells more frequently, while increasing your mana pool ensures that you don't run out too quickly, giving you a steady flow of resources.

3. Cooldown Reduction + Mana Regeneration
Cooldown Reduction: Reduces the cooldown of your abilities, letting you use them more often.

Mana Regeneration: Increases the rate at which you regenerate mana, allowing you to cast more spells without worrying about running out of resources.

Why it works: The synergy between cooldown reduction and mana regeneration makes it possible for you to consistently use your abilities in battle, even during longer encounters. You’ll be able to spam spells more freely while your mana recharges faster.

4. Resource Cost Reduction + Life on Hit
Resource Cost Reduction: Reduces the resource cost of your abilities, allowing you to cast more spells with fewer resources.

Life on Hit: Restores life each time you land a hit, which can help keep you alive as you focus on managing your resources.

Why it works: Resource cost reduction allows you to keep your resource usage low, while life on hit ensures that you maintain survivability during combat. This is particularly useful for hybrid builds that combine damage dealing with sustain in the form of healing.

5. Mana Regeneration + Vitality
Mana Regeneration: Increases how quickly you regenerate mana, letting you use your abilities more frequently.

Vitality: Increases your health pool, improving your survivability while focusing on resource management.

Why it works: This combination boosts mana regeneration, allowing you to use your abilities more often, while vitality ensures that you're not as vulnerable when your resource pool is low or when you're caught in close combat.

6. Resource Generation + Critical Hit Chance
Resource Generation: Increases how quickly you generate resources, such as mana or fury.

Critical Hit Chance: Increases the chance of landing critical hits, which can provide additional benefits like damage or resource regeneration.

Why it works: If your critical hits also grant additional resource generation (common for certain builds), this combination ensures that your resources are replenished as you deal damage. You’ll be able to keep your spells flowing with minimal downtime while dealing more damage.

7. Cooldown Reduction + Damage Buffs
Cooldown Reduction: Allows you to cast abilities more frequently by reducing their cooldowns.

Damage Buffs: Increases the damage of your abilities, making them more effective when you can cast them faster.

Why it works: This combination increases your damage output by allowing you to spam powerful abilities. While your resource management may still be a factor, damage buffs ensure that your spells hit harder when you do use them.

8. Mana Cost Reduction + Resource Cost Reduction
Mana Cost Reduction: Reduces the mana cost of your abilities, allowing you to cast spells more efficiently.

Resource Cost Reduction: Reduces the cost of other resources (such as fury or energy), giving you the freedom to use your abilities without draining any one resource pool.

Why it works: This combination makes you much more efficient at using your abilities by reducing both the mana cost and the cost of other resources, allowing you to sustain a longer barrage of attacks or spells with minimal downtime.

9. Resource Generation + Life per Kill
Resource Generation: Increases how quickly you generate resources (mana, fury, etc.), ensuring you're always able to cast your spells.

Life per Kill: Restores health with each kill, providing you with sustain during combat, especially during mob fights or when you need to deal with large groups of enemies.

Why it works: This combination lets you sustain through long fights while keeping your resources at full capacity. As you kill enemies, you'll regenerate health, which supports your resource management and survival simultaneously.

10. Resource Cost Reduction + Increased Damage
Resource Cost Reduction: Reduces the cost of your abilities, which lets you cast more spells or use abilities without draining your resources.

Increased Damage: Boosts the damage output of your abilities, ensuring that each resource expenditure is worth it.

Why it works: Resource cost reduction allows you to use more abilities, and increased damage ensures that those abilities hit harder, making this combination perfect for damage-dealing casters who need to manage their resources effectively while maximizing damage output.

Conclusion:
In Diablo IV, resource management is a key component for casters and hybrid builds. These affix combinations allow you to sustain your abilities, reduce costs, and regenerate resources efficiently, ensuring that you can keep your powerful spells and abilities flowing throughout combat. Experiment with different combinations based on your class and Diablo 4 admissions playstyle to find the perfect balance for your mana, fury, or any other resource you rely on.